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<DIV><FONT face=Arial size=2>Hello everybody,</FONT></DIV>
<DIV><FONT face=Arial size=2>I have to do a nucleophilic substitution between a
primary amine and a mesylate of an alcohol. Actually I use 1eq of the
mesylate alcohol and 2 eq of the amine (1 eq as base and 1 eq for the
reaction).</FONT></DIV>
<DIV><FONT face=Arial size=2>I want to use only 1 eq of this amine but I need a
base. The problem is that I don't want to do elimination, only substitution
because I have an asymetry center on the carbon on beta position and I don't
want to racemize.</FONT></DIV>
<DIV><FONT face=Arial size=2>I tied triethylamine in toluene, but I haven't good
result.</FONT></DIV>
<DIV><FONT face=Arial size=2>If anybody can help me!!!</FONT></DIV>
<DIV><FONT face=Arial size=2>Thanks.</FONT></DIV>
<DIV><FONT face=Arial size=2></FONT> </DIV>
<DIV><FONT face=Arial size=2></FONT> </DIV>
<DIV><FONT face=Arial size=2>
Stephanie</FONT></DIV></BODY></HTML>